Pfizer Other Medical Information — General gluten content of Pfizer prescription products

Print this page | Cancel

New user?

Benefits of Registration

Returning user?

E-Mail:

Password:

Forgot My Password

Patient Education Materials

Patient Assistance Programs

Clinical Trials

Pipeline

Pfizer Contacts

Pfizer Medical Information
(Search Medical Responses)

WyethHCP.com
(Access Wyeth for Professionals)

Explore Other Online Resources

Prescribing Information

Pfizer Other Medical Information — General gluten content of Pfizer prescription products


	Return to the LIPITOR Product Center

Please note that Pfizer Inc lists active and most inactive ingredients in the package inserts or on the product containers. Inactive ingredients present in trace amounts (e.g., imprint ink) may not be listed. The accuracy of our statements is based upon the final product composition formula only and cannot guarantee that minute amounts of substances are not contained in raw materials obtained from various suppliers for our manufacturing process.

Gluten is a mixture of two proteins, gliadin and glutenin, that are present in wheat flour and to a lesser extent in barley, oats, and rye.¹

The Pfizer U.S. pharmaceutical products in Table 1 below do not list wheat, barley, oats, and/or rye as ingredients. Please note that Table 1 does not contain a complete listing of all Pfizer pharmaceutical products

Table 1. Pfizer U.S. Pharmaceutical Products That Do NOT list Wheat, Barley, Oats, and/or Rye as Ingredients

Accupril^® (quinapril HCl) Tablets²
Aldactone^® (spironolactone) Tablets²
Aldactazide^® (spironolactone/hydrochlorothiazide) Tablets²
Aricept^® (donepezil HCl) Tablets²
Aricept^® ODT (donepezil HCl, orally disintegrating) Tablets²
Aromasin^® (exemestane) Tablets²
Arthrotec^® (diclofenac sodium/misoprostol) Tablets²
Azulfidine^® (sulfasalazine) Tablets²
Azulfidine EN-tabs^® (sulfasalazine, delayed release) Tablets²
Cardura^®XL (doxazosin mesylate, extended release) Tablets²
Celebrex^® (celecoxib) Capsules²
Chantix^® (varenicline) Tablets²
Colestid^® (colestipol HCl) Tablets, Granules²
Cleocin^® (clindamycin hydrochloride) Capsules²
Cortef^® (hydrocortisone) Tablets²
Detrol^® (tolterodine) Tablets²
Detrol^®LA (tolterodine, extended release) Capsules²
Diflucan^® (fluconazole) Tablets, Oral Suspension²
Dilantin^® (phenytoin) Infatabs, Kapseals, Oral Suspension²
Dostinex^® (cabergoline) Tablets²
Estring^® (estradiol) Vaginal Ring²
Exubera^® (insulin human [rDNA origin]) Inhalation Powder²
Geodon^® (ziprasidone HCl) Capsules²
Glucotrol^® (glipizide) Tablets²
Glucotrol XL^® (glipizide, extended release) Tablets²
Glyset^® (miglitol) Tablets²
Inspra^® (eplerenone) Tablets²
Lipitor^® (atorvastatin calcium) Tablets²
Lomotil^® (diphenoxylate hydrochloride/atropine sulfate) Tablets, Liquid²
Lyrica^® (pregabalin) Capsules²
Medrol^® (methylprednisolone) Tablets²
Micronase^® (glyburide) Tablets²
Minizide^® (prazosin hydrochloride/polythiazide) Capsules²
Nardil^® (phenelzine sulfate) Tablets²
Neurontin^® (gabapentin) Capsules, Tablets, Oral Solution²
Norvasc^® (amlodipine besylate) Tablets²
Relpax^® (eletriptan hydrobromide) Tablets²
Revatio^™ (sildenafil citrate) Tablets²
Sutent^® (sunitinib malate) Capsules²
Vantin^® (cefpodoxime proxetil) Tablets, Oral Suspension²
Vfend^® (voriconazole) Tablets and Oral Suspension²
Viagra^® (sildenafil citrate) Tablets²
Vibramycin^® (doxycycline calcium) Oral Syrup²
Vibramycin^® (doxycycline hyclate) Capsules²
Vibramycin^® (doxycycline monohydrate) Oral Suspension²
Vibra-Tabs^® (doxycycline hyclate) Film Coated Tablets²
Zithromax^® (azithromycin) Tablets and Oral Suspension (all strengths)^2,3
Zmax^® (azithromycin, extended release) Oral Suspension²
Zoloft^® (sertraline HCl) Tablets, Oral Concentrate²
Zyrtec^® (cetirizine HCl) Tablets⁴
Zyrtec^® (cetirizine HCl) Chewable Tablets⁴
Zyrtec^® (cetirizine HCl) Oral Syrup²
Zyrtec-D 12 Hour^® (cetirizine HCl/pseudoephedrine HCl, extended release) Tablets²
Zyvox^® (linezolid) Tablets, Oral Suspension²

The Pfizer U.S. pharmaceutical products in Table 2 below contain gluten as an ingredient. Please note that Table 2 does not contain a complete listing of all Pfizer pharmaceutical products.

Table 2. Pfizer U.S. Pharmaceutical Products That Contain Gluten as an Ingredient

Halcion^® (triazolam) Tablets²
Xanax^® (alprazolam) Tablets²
Xanax XR^® (alprazolam, extended release) Tablets²

1. Sweetman SC. Martindale: The Complete Drug Reference. 33rd ed. London, UK: Pharmaceutical Press, 2002.
2. Data on file (35) - Pfizer Inc.
3. Data on file (38) - Pfizer Inc.
4. Data on file (36) - Pfizer Inc.

PRINTER-FRIENDLY

LIPITOR Safety Information

LIPITOR (atorvastatin calcium) Indication Statement

LIPITOR is indicated as an adjunct to diet to reduce the risk of myocardial infarction (MI), stroke, revascularization procedures, and angina in adult patients with multiple risk factors but without clinically evident coronary heart disease (CHD); to reduce the risk of MI and stroke in patients with type 2 diabetes and without clinically evident CHD, but with multiple risk factors; to reduce the risk of nonfatal MI, fatal and nonfatal stroke, revascularization procedures, hospitalization for congestive heart failure, and angina in adult patients with clinically evident CHD.

LIPITOR, as an adjunct to diet, is also indicated to reduce elevated total-C, LDL-C, apo B, and TG levels; and to increase HDL-C in patients with primary hypercholesterolemia (heterozygous familial and nonfamilial) and mixed dyslipidemia.

Important Safety Information

LIPITOR is contraindicated in patients with active liver disease or unexplained persistent elevations of hepatic transaminases; in women who are or may become pregnant or who are nursing; in patients with hypersensitivity to any component of this medication.

Rare cases of rhabdomyolysis have been reported with LIPITOR and other statins. Tell patients to promptly report muscle pain, tenderness, or weakness. Predisposing factors include advanced age (≥65), uncontrolled hypothyroidism, and renal impairment. Patients with a history of renal impairment merit closer monitoring. In cases of myopathy or rhabdomyolysis, therapy should be temporarily withheld or discontinued.

The concomitant use of higher doses of atorvastatin with certain drugs such as cyclosporine and strong CYP3A4 inhibitors (eg, clarithromycin, itraconazole, and HIV protease inhibitors) increases the risk of myopathy/rhabdomyolysis. Lower doses of LIPITOR should be considered. Physicians should carefully monitor patients for signs or symptoms of myopathy early during therapy and when titrating the dose of either drug.

It is recommended that liver function tests be performed prior to and 12 weeks following both the initiation of therapy and any elevation of dose, and periodically thereafter. If ALT or AST values >3 x ULN persist, dose reduction or withdrawal is recommended.

In a post hoc analysis of the SPARCL study in patients without CHD who had a stroke or TIA within the preceding 6 months, a higher incidence of hemorrhagic stroke was seen in the LIPITOR 80-mg group compared with placebo (2.3% vs 1.4%). Some baseline characteristics, including hemorrhagic and lacunar stroke on study entry, were associated with a higher incidence of hemorrhagic stroke in the atorvastatin group.

The most commonly reported adverse reactions with LIPITOR in placebo-controlled trials were: nasopharyngitis, arthralgia, diarrhea, pain in extremity, and urinary tract infection.

Please see full prescribing information.

LIPITOR^® (atorvastatin calcium) tablets

lipitor_safety_information.htm