Important Safety Information
Rebif should be used with caution in patients with depression, preexisting seizure
disorders, and hepatic dysfunction. The potential for liver injury should be considered
when used in combination with other products associated with liver injury. Anaphylaxis
and other allergic reactions (some severe) have been reported as a rare complication
of Rebif. Female patients should be warned about the potential risk of miscarriage;
discontinuation should be considered if pregnancy occurs.
Potential serious side effects with Rebif include hepatic dysfunction, depression,
risk to pregnancy, allergic reactions, and injection-site reactions.
The most common side effects with Rebif are injection-site reactions, flu-like symptoms,
depression, abdominal pain, elevated liver enzymes, and blood abnormalities.
Patients should be instructed to read the Medication Guide accompanying the product.
This information is intended only for health care professionals in the United States.
Rebif is a registered trademark of EMD Serono, Inc.
Copyright 2007 EMD Serono, Inc. All rights reserved.