Improvement in the overall HAM-D₂₁ anxiety/somatization factor score²

*P=0.001
Average daily dose was 148.8 mg.
Last-observation-carried-forward (LOCF) analysis.
A pooled analysis of 22 depression trials (N=5,071) in patients treated with EFFEXOR or EFFEXOR XR. The anxiety/somatization factor included the following HAM-D₂₁ items: 10 (anxiety–psychic), 11 (anxiety–somatic), 12 (somatic–GI), 13 (somatic–general), 15 (hypochondriasis), and 17 (insight).

Improvement in the overall HAM-D21 anxiety/somatization factor score2