Patient profiles

Learn more about adult patients who may be appropriate candidates for vaccination with Prevnar 13®
These patient profiles are hypothetical in nature and are not meant to represent specific individuals.
Aged 65 and older in good health
Medical history
  • Does yoga 5 days per week
  • Has mildly elevated cholesterol, currently managed with diet and exercise
  • Pneumococcal vaccine naïve
Risk factors for pneumococcal pneumonia
1.65 years of age
Healthy adults aged 65 and older can face a 3.8x greater risk for pneumococcal pneumonia vs healthy 18- to 64-year-olds3
Because Nancy is 65 years of age and is pneumococcal vaccine naïve, Prevnar 13® is recommended by the CDC based on shared clinical decision-making. When the decision to administer Prevnar 13® is made, it should be given first in series with Pneumovax 23®. Pneumovax 23® is routinely recommended in this patient.1
 
Aged 65 and older with diabetes
Medical history
  • Diagnosed with type 2 diabetes at 55 years of age
  • Vaccinated with PPSV23 at diagnosis
Risk factors for pneumococcal pneumonia
1. 67 years of age
2. Diabetes
Adults aged 65 and older with diabetes can face a 2.8x greater risk for pneumococcal pneumonia vs healthy adults aged 65 and older3
Because Iris is 67 years of age and also has diabetes, she is at increased risk for pneumococcal pneumonia. Prevnar 13® is recommended by the CDC based on shared clinical decision-making. When the decision to administer Prevnar 13® is made, it should be given first in series with Pneumovax 23® at least one year apart.1 Pneumovax 23® is routinely recommended in adults 65 and older.
 
Aged 65 and older with chronic heart disease (CHD)
Medical history
  • Current smoker diagnosed with CHD at the age of 63
  • Recently retired, but remains active
  • Pneumococcal vaccine naïve
Risk factors for pneumococcal pneumonia
1. 65 years of age
2. Current smoker
3. CHD
Adults aged 65 and older with with two underlying medical conditions can face a 4.2x greater risk for pneumococcal pneumonia vs healthy adults aged 65 and older1
Because Ernie is 65 years of age, a current smoker, and also has a CHD diagnosis, he is at increased risk for pneumococcal pneumonia. Prevnar 13® is recommended by the CDC based on shared clinical decision-making. When the decision to administer Prevnar 13® is made, it should be given first in series with Pneumovax 23®. Pneumovax 23® is routinely recommended in this patient.1
 
Chronic obstructive pulmonary disease (COPD) on high-dose oral corticosteroids (OCS)
Medical history
  • Diagnosed with COPD at the age of 50 years
  • Vaccinated with PPSV23 at the time of diagnosis
  • Prevnar 13® naïve 
  • Currently treated with high-dose OCS
Risk factors for pneumococcal pneumonia
1. Diagnosis of COPD 
2. Currently treated with high-dose OCS 
3. Chronic/current smoker
Adult patients under 65 taking immunosuppressive medications such as high-dose OCS can face a 7.5x greater risk for pneumococcal pneumonia vs
age-matched
controls3
Due to Timothy’s immunosuppressive treatment for his COPD, the CDC’s ACIP recommends that he receive 2 different pneumococcal vaccinations in series, starting with Prevnar 13®1 
Timothy has already received PPSV23 and is now due to receive Prevnar 13®
 
Rheumatoid arthritis (RA) on disease-modifying antirheumatic drugs (DMARDs)
Medical history
  • Diagnosed with RA
  • Initiating treatment with DMARDs
  • Pneumococcal vaccine naïve
Risk factors for pneumococcal pneumonia
1. Initiating treatment with DMARDs
Adult patients under 65 taking immunosuppressive medications such as DMARDs can face a 7.5x greater risk for pneumococcal pneumonia vs
age-matched
controls3
Due to Debbie’s immunosuppressive treatment for her RA, the CDC’s ACIP recommends that she receive 2 different pneumococcal vaccinations in series, starting with Prevnar 13®1 
 
Chronic renal failure (CRF)
Medical history
  • Diagnosed with CRF
  • Treated with dialysis for the past 18 months
  • Diagnosed with diabetes at the age of 38 years
  • Pneumococcal vaccine naïve
Risk factors for pneumococcal pneumonia
1. Diagnosis of CRF
2. Diagnosis of diabetes
Adult patients under 65 with CRF can face a ​14.4x greater risk for pneumococcal pneumonia vs
age-matched
controls3
Due to Jeffrey’s CRF, the CDC’s ACIP recommends that he receive 2 different pneumococcal vaccinations in series, starting with Prevnar 13®1 
 
ACIP=Advisory Committee on Immunization Practices; CDC=Centers for Disease Control and Prevention; CHD=chronic heart disease; PPSV23=23-valent pneumococcal polysaccharide vaccine.
References:
  1. Matanock A, Lee G, Gierke R, Kobayashi M, Leidner A, Pilishvili T. Use of 13-valent pneumococcal conjugate vaccine and 23-valent pneumococcal polysaccharide vaccine among adults aged ≥65 years: updated recommendations of the Advisory Committee on Immunization Practices. MMWR Morb Mortal Wkly Rep. 2019;68:1069-1075. doi: http://dx.doi.org/10.15585/mmwr.mm6846a5.
  2. Department of Health & Human Services (DHHS). CMS Manual System. Pub 100-02 Medicare Benefit Policy. Transmittal 202. http://www.cms.gov/Regulations-and-Guidance/Guidance/Transmittals/Downloads/R202BP.pdf. Accessed January 7, 2020.
  3. Shea KM, Edelsberg J, Weycker D, Farkouh RA, Strutton DR, Pelton SI. Rates of pneumococcal disease in adults with chronic medical conditions. Open Forum Infect Dis. 2014;1-9. doi:10.1093/ofid/ofu024.