Adhesion Strength and Flexibility

Adhesion Strength and Flexibility
SurgiSeal Stylus—Proven adhesion strength and flexibility1-7*
Adhesion strength and flexibility of SurgiSeal Stylus were shown to be comparable to Dermabond® in the standardized tests below1-7
Mechanical Performance Testing: SurgiSeal Topical Skin Adhesive vs Dermabond®1-7
  Mean Values
[where applicable]
Comparable Values
to Dermabond®
Lap-Shear
Tensile Loading
SurgiSeal—14.48 lb/in sq
Dermabond®—15.68 lb/in sq
Adhesive & Sealant
Wound Strength
Under Tension
SurgiSeal—2.67 lb
Dermabond®—2.36 lb
T-Peel
Tension Loading§
SurgiSeal—39.6 lb
Dermabond®—27.1 lb
Strength Under
Tension Loading||
SurgiSeal—14.16 lb/in sq
Dermabond®—10.88 lb/in sq
Mandrel Bend
Flexibility Testing
All Samples Passed
*Mechanical Performance Testing is not necessarily indicative of clinical outcomes and performance.
Test adhered to protocol ASTM F 2255-05, Standard Test Method for Strength Properties of Tissue Adhesives in Lap-Shear by Tension Loading.3
Test adhered to protocol ASTM F 2458-05, Standard Test Method for Wound Closure Strength of Tissue Adhesives and Sealants.4
§Test adhered to protocol ASTM F 2256-05, Standard Test Method for Strength Properties of Tissue Adhesives in T-Peel by Tension Loading.5
||Test adhered to protocol ASTM F 2258-05, Standard Test Method for Strength Properties of Tissue Adhesives in Tension.6
Test adhered to protocol ASTM D 4338-97, Standard Test Method for Flexibility Determination of Supported Adhesive Films by Mandrel Bend.7
Dermabond® is a registered trademark of Ethicon US, LLC.
Full apposition strength is expected to be achieved in about 60 seconds, and completely dry in 5 minutes after the final layer is applied.8
SURGISEAL Stylus has been shown with in vitro studies to provide a strong holding strength of approximated wound skin edges. It has been shown to achieve full strength in one minute and completely dry in five minutes.
Flexibility without a plasticizer1
SurgiSeal offers flexibility without a plasticizer
  • Formulation of the topical skin adhesive within SurgiSeal products is 99% 2-octyl cyanoacrylate combined with a preservative (BHA) and a purple colorant
References: 1. US Food and Drug Administration. SURGISEAL Topical Skin Adhesive 510(k); May 30, 2008. 2. Adhezion Biomedical. SURGISEAL Stylus and Stylus Twist Topical Skin Adhesive abbreviated 510(k); May 2013. 3. ASTM International. ASTM F 2255-05. Standard Test Method for Strength Properties of Tissue Adhesives in Lap-Shear by Tension Loading. 2005. 4. ASTM International. ASTM F 2458-05. Standard Test Method for Wound Closure Strength of Tissue Adhesives and Sealants. 2005. 5. ASTM International. ASTM F 2256-05. Standard Test Method for Strength Properties of Tissue Adhesives in T-Peel by Tension Loading. 2005. 6. ASTM International. ASTM 2258-05. Standard Test Method for Strength Properties of Tissue Adhesives in Tension. 2005. 7. ASTM International. ASTM D 4338-97. Standard Test Method for Flexibility Determination of Supported Adhesive Films by Mandrel Bend. Reapproved 2004. 8. SURGISEAL Stylus Topical Skin Adhesive (2-octyl cyanoacrylate) [instructions for use]. Adhezion Biomedical, LLC; July 2015.